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Baby KJ no longer needs a liver transplant
In clinical trials, discontinuation rates due to gastrointestinal adverse effects ranged from 3-7%, indicating that whilst most patients can tolerate these symptoms, they can be sufficiently troublesome to necessitate treatment cessation in some cases
BioFactors 8:2732
Patients should be counseled to: Consume smaller, more frequent meals (56 per day) rather than large portions Emphasize low-fat, low-fiber foods that empty more readily from the stomach Ensure adequate hydration, particularly with liquid calories if solid food tolerance is poor Avoid lying down immediately after meals Chew food thoroughly and eat slowly For patients developing concerning symptoms, temporary dose reduction or treatment interruption may be necessary
Only one thing is for certain: even if GLP-1s go out of style, the associated culture of being skinny, regardless of health risks, is here to stay
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