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Four proline residues, including an unusual triple-proline sequence, confer resistance to enzymatic degradation

45 Currently, the strategy of multiple receptor stimulation is actively expanding indications in metabolic disorders, particularly in MASLD, and some medications have reported more potent therapeutic efficacy compared to single GLP-1RA

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This means you can take your first dose in less than a week

This will inevitably result in a severe IGF-1 deficiency, together with high GH levels, very far into the acromegaly range [25]