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Weeks 5-8: Weight Loss Becomes More Noticeable For many individuals, the second month is when measurable weight loss becomes more consistent

The correct dose will help you lose weight consistently at a healthy rate, approximately 1 to 2 pounds per week, and minimize side effects

In a later interview with People , published in December 2025, Winfrey revealed that just six months after starting GLP-1s, shed decided to see if she could beat the medication by stopping taking them

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He has also written several books, including The MindBody Workbook