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By enhancing ER protein-folding capacity, reducing the accumulation of misfolded proteins, and activating adaptive signaling programs, the UPR allows cancer cells to survive and proliferate in hostile microenvironments that would otherwise compromise cellular viability

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Cells were pelleted by centrifugation for 5 min at 800 g at 4 C

The Strengthening Phase: Weeks 58 By weeks 58 in the BPC-157 timeline, tissue strength and load tolerance begin returning